Acelyrin, Inc. (SLRN) Research

Acelyrin, Inc. is a biopharmaceutical company focused on discovering, obtaining, and rapidly advancing the development and commercialization of innovative medical therapies. The firm's most advanced experimental drug is izokibep, a potent small protein therapeutic specifically designed to block IL-17A. This compound is currently undergoing Phase 3 clinical evaluations for its use in treating Hidradenitis Suppurativa, Psoriatic Arthritis, and uveitis. Additionally, izokibep is being assessed in Phase 2 clinical trials for Axial Spondyloarthritis. Beyond izokibep, Acelyrin is also developing lonigutamab, a humanized immunoglobulin G1 (IgG1) monoclonal antibody that targets the insulin-like growth factor 1 receptor. Lonigutamab is in Phase 1 clinical studies for individuals with thyroid eye disease. Furthermore, the company has SLRN-517, a fully human IgG1 monoclonal antibody aimed at c-KIT, which is in the preclinical stage of development for the treatment of chronic urticaria. Founded in 2020, Acelyrin's corporate headquarters are located in Agoura Hills, California.

Market snapshot

Symbol
SLRN
Price
$2.27
Day change
0.00%
Market cap
$229.2M
P/E ratio
-1.70x
52-week range
1.845-7.25
Sector
Healthcare
Industry
Biotechnology
Analyst price target
$10.50

Peer companies

  • Catabasis Pharmaceuticals, Inc. (CATB)
  • Cytocom, Inc. (CBLI)
  • Celularity Inc. (CELU)
  • CARGO Therapeutics, Inc. Common Stock (CRGX)
  • Inhibrx Biosciences, Inc. (INXB)
  • Inozyme Pharma, Inc. (INZY)
  • Merrimack Pharmaceuticals, Inc. (MACK)
  • Spectrum Pharmaceuticals, Inc. (SPPI)

Recent insider activity

  • AyurMaya Capital Management Company, LP — D-Return (9334735 shares) on 2025-05-21
  • Kim Mina — A-Award (89526 shares) on 2025-05-21
  • Kim Mina — D-Return (190114 shares) on 2025-05-21
  • Kim Mina — D-Return (770833 shares) on 2025-05-21
  • Kim Mina — D-Return (1195856 shares) on 2025-05-21

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