Scilex Holding Company (SCLX) Research

Scilex Holding Company is a biopharmaceutical enterprise that specializes in the development and market introduction of non-opioid therapies designed to alleviate both acute and chronic pain. Its primary marketed offering is ZTlido 1.8%, a topical prescription formulation of lidocaine specifically engineered to mitigate neuropathic discomfort associated with post-herpetic neuralgia, a condition characterized by persistent nerve pain following shingles. Beyond this, the company's development pipeline includes SP-102, a viscous gel corticosteroid for epidural administration, currently undergoing Phase III trials for lumbosacral radicular pain. Another candidate, SP-103, is progressing through Phase II trials for managing low back pain. Furthermore, SP-104, a novel, low-dose, delayed-release naltrexone hydrochloride formulation, has successfully concluded Phase I clinical testing for the treatment of fibromyalgia. Its corporate offices are situated in Palo Alto, California. Scilex Holding Company operates as a subsidiary of Sorrento Therapeutics, Inc.

Market snapshot

Symbol
SCLX
Price
$7.47
Day change
+7.64%
Market cap
$63.4M
P/E ratio
-0.12x
52-week range
2.61519-21.33873
Sector
Healthcare
Industry
Drug Manufacturers - General
Next earnings
in 2 months

Peer companies

  • Acumen Pharmaceuticals, Inc. (ABOS)
  • Agenus Inc. (AGEN)
  • Alector, Inc. (ALEC)
  • Citius Oncology, Inc. (CTOR)
  • Inovio Pharmaceuticals, Inc. (INO)
  • Opus Genetics, Inc. (IRD)
  • Incannex Healthcare Limited (IXHL)
  • Lucid Diagnostics Inc. (LUCD)

Recent insider activity

  • Ma Stephen Hoi — P-Purchase (650000 shares) on 2026-04-17
  • Ji Henry — P-Purchase (3250000 shares) on 2026-04-16
  • Ji Henry — S-Sale (650000 shares) on 2026-04-17
  • Scilex Holding Co — S-Sale (3689016 shares) on 2025-12-26
  • Scilex Holding Co — S-Sale (7310984 shares) on 2025-12-29

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