MBX Biosciences, Inc. Common Stock (MBX) Research

MBX Biosciences, Inc. is a biopharmaceutical company in its clinical development phase, dedicated to pioneering precise peptide-based therapies for endocrine and metabolic conditions. Its most advanced drug candidate, MBX 2109, is a parathyroid hormone peptide prodrug currently in Phase 2 clinical trials. This medication is being evaluated as a long-duration hormone replacement treatment for individuals suffering from chronic hypoparathyroidism. The company is also progressing with MBX 1416, a prolonged-action glucagon-like peptide-1 (GLP-1) receptor antagonist, which is undergoing Phase 1 clinical assessment. The aim of this therapy is to address post-bariatric hypoglycemia, a persistent complication often seen after weight-loss surgery. Furthermore, MBX Biosciences is developing MBX 4291, a key candidate for obesity treatment. This highly potent and long-acting prodrug functions as a co-agonist for both GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptors. It is currently in investigational new drug (IND)-enabling studies, with the intention of treating obesity and its associated health issues. Founded in 2018, the company's operations are headquartered in Carmel, Indiana.

Market snapshot

Symbol
MBX
Price
$43.03
Day change
+3.46%
Market cap
$1.4B
P/E ratio
-23.14x
52-week range
9.43-45.85
Sector
Healthcare
Industry
Biotechnology
Next earnings
in 2 months
Analyst price target
$68.80

Recent news

  • MBX Biosciences Highlights Sustained Calcium Control In Rare Disease

    MBX Biosciences Inc. (NASDAQ:MBX) on Thursday reported full results from its 12-week Avail Phase 2 trial and new one-year data from an ongoing open-label extension study of once-weekly canvuparatide in adults with chronic hypoparathyroidism.

Peer companies

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  • ArriVent BioPharma, Inc. Common Stock (AVBP)
  • Ginkgo Bioworks Holdings, Inc. (DNA)
  • Erasca, Inc. (ERAS)
  • Iovance Biotherapeutics, Inc. (IOVA)
  • MeiraGTx Holdings plc (MGTX)
  • MoonLake Immunotherapeutics (MLTX)
  • Replimune Group, Inc. (REPL)

Recent insider activity

  • Mathers Edward T — A-Award (12500 shares) on 2026-06-04
  • Pescovitz Ora H. — A-Award (12500 shares) on 2026-06-04
  • Heron Patrick J — A-Award (12500 shares) on 2026-06-04
  • Stelzer Laurie — A-Award (12500 shares) on 2026-06-04
  • Hoerter Steven L. — A-Award (12500 shares) on 2026-06-04

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