Hillstream BioPharma, Inc. (HILS) Research

Hillstream BioPharma, Inc. is a pre-clinical stage biotechnology firm committed to creating groundbreaking therapeutic options. Its core mission is to exploit ferroptosis, an anti-cancer pathway that initiates iron-mediated cell death (IMCD), specifically to address cancers that are resistant to conventional treatments. The company's developmental pipeline features several key candidates: HSB-1216: An IMCD inducer currently under development for solid tumor indications. HSB-888: An IMCD inducer incorporating an anthracycline analogue, delivered via a dual Quatramer system, also aimed at solid tumors. HSB-510: A targeted bifunctional inhibitory compound, encapsulated within the Quatramer delivery system, which demonstrates remarkable potency (single-digit nanomolar IC50) against both PI3K-delta and HDAC6, targets recognized for their role in downregulating cellular processes. HSB-114: An immunotherapeutic agent that leverages the proprietary Quatramer technology to precisely deliver the tumor necrosis factor-alpha gene into cancer cells. Established in 2017, the company's operations are based in Bridgewater, New Jersey.

Market snapshot

Symbol
HILS
Price
$0.24
Day change
+5.66%
Market cap
$4.2M
P/E ratio
-0.61x
52-week range
0.1723-2.65
Sector
Healthcare
Industry
Biotechnology

Peer companies

  • Aptose Biosciences Inc. (APTO)
  • Atreca, Inc. (BCEL)
  • Altamira Therapeutics Ltd. (CYTO)
  • Gamida Cell Ltd. (GMDA)
  • Gritstone bio, Inc. (GRTS)
  • Nabriva Therapeutics plc (NBRVF)
  • Onconetix, Inc. (ONCO)
  • TNF Pharmaceuticals, Inc. (TNFA)

Recent insider activity

  • MILBY RANDY — P-Purchase (29000 shares) on 2023-12-15
  • MILBY RANDY — P-Purchase (10000 shares) on 2023-11-30
  • Bui Lynne A. — A-Award (25000 shares) on 2023-11-07
  • Appajosyula Sireesh — A-Award (25000 shares) on 2023-11-07
  • Anderson Kelly — A-Award (50000 shares) on 2023-11-07

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