Castle Biosciences, Inc. (CSTL) Research

Castle Biosciences, Inc. functions as a commercial-stage diagnostics firm, with its primary objective being the provision of both diagnostic and prognostic testing services, specifically targeting various dermatological cancers. Their flagship product, DecisionDx-Melanoma, represents an advanced multi-gene expression profile (GEP) assay engineered to assess the probability of metastasis in patients afflicted with invasive cutaneous melanoma. In addition to their leading solution, the company has created several other specialized, proprietary tests. Among these is DecisionDx-UM, a GEP test tailored to forecast the risk of metastasis for individuals with uveal melanoma, a less common malignancy of the eye. Another key offering is DecisionDx-SCC, a distinctive 40-gene expression profile test that utilizes a patient's unique tumor biology to predict their specific risk of squamous cell carcinoma metastasis, particularly for those presenting with recognized risk factors. Moreover, they offer DecisionDx DiffDx-Melanoma and myPath Melanoma, both proprietary GEP tests employed to assist in the accurate diagnosis of ambiguous pigmented lesions. These specialized testing services are provided by Castle Biosciences to patients predominantly through their healthcare providers. The organization commenced operations in 2007 and maintains its corporate headquarters in Friendswood, Texas.

Market snapshot

Symbol
CSTL
Price
$21.12
Day change
+4.30%
Market cap
$640.6M
P/E ratio
-49.19x
52-week range
14.59-44.28
Sector
Healthcare
Industry
Medical - Diagnostics & Research
Next earnings
in 1 month
Analyst price target
$43.50

Peer companies

  • AMN Healthcare Services, Inc. (AMN)
  • CareDx, Inc (CDNA)
  • DarioHealth Corp. (DRIO)
  • Embecta Corp. (EMBC)
  • Evolent Health, Inc. (EVH)
  • Fulgent Genetics, Inc. (FLGT)
  • Geron Corporation (GERN)
  • Myriad Genetics, Inc. (MYGN)

Recent insider activity

  • Oelschlager Kristen M — S-Sale (8587 shares) on 2026-06-16
  • MAETZOLD DEREK J — M-Exempt (550 shares) on 2026-06-15
  • MAETZOLD DEREK J — S-Sale (1357 shares) on 2026-06-15
  • MAETZOLD DEREK J — S-Sale (1153 shares) on 2026-06-15
  • MAETZOLD DEREK J — M-Exempt (550 shares) on 2026-06-15

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